This post may contain affiliate links. Please read our disclosure policy.

John Wayne Casserole

Recipe by Julia Pacheco

4.5 from 26 votes

Course: MainCuisine: AmericanDifficulty: Easy

Servings

servings

Prep time

minutes

Cooking time

minutes

Yummy biscuit crust is topped with delicious layers of ground beef, veggies, and lots and lots of cheese. This John Wayne Casserole will become a family favorite!

Cook Mode

Keep the screen of your device on

Ingredients

1 lb ground beef
1/2 white onion, diced
1 1/2 tbsp taco seasoning
1/4 cup water
1 can Rotel Diced Tomatoes and Green Chiles
1 can corn, drained
1 cup shredded sharp cheddar cheese
1 cup mozzarella cheese
Bisquick Mixture
2 cups Bisquick
1 cup water
Creamy Mixture
1/4 cup mayonnaise
7.5 oz chive and onion cream cheese
1/8 tsp pepper
1/8 tsp garlic powder
Toppings (optional)
chopped cherry tomatoes
sour cream
more cheese
cilantro

Directions

Preheat oven to 325℉.
Add the ground beef and onion to a skillet over medium-high heat, and cook until the beef is cooked through. Remove any excess grease, then add in the taco seasoning and water and simmer for 3 minutes. Add in the can of Rotel, can of corn, and stir to combine.
Make the Bisquick mixture by combining the Bisquick and water in a small bowl. Stir until well combined and set aside.
Whisk the ingredients for the creamy mixture together in a small bowl. Set aside.
Grease a 9×13 baking dish with non-stick spray. Spread the Bisquick mixture evenly in the bottom of the pan. Pour the ground beef mixture on top, then spread the creamy mixture over the ground beef, then sprinkle with the cheddar and mozzarella. Bake for 40 minutes. Let sit for 10 minutes. Top with your favorite toppings and enjoy!